USP9X-RBBP7 Fusion FISH Probe
The USP9X-RBBP7 Fusion FISH Probe is used to confirm a fusion of the USP9X and RBBP7 genes. The fusion of the USP9X and RBBP7 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP9X-RBBP7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-RERE | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-REOR | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-REGO | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-REGR | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-REAQ | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-ORRE | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-OROR | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-ORGO | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-ORAQ | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-GORE | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-GOOR | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-GOGO | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-GOGR | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-GOAQ | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-GRRE | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-GROR | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-GRGO | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-GRGR | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-GRAQ | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-AQRE | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-AQOR | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-AQGO | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-AQGR | 20 (40 μL) | 200 μL |
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| USP9X-RBBP7-20-AQAQ | 20 (40 μL) | 200 μL |
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RBBP7 Gene Summary
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Gene Name: RB Binding Protein 7, Chromatin Remodeling Factor
Chromosome: CHRX: 16862774 -16888534
Locus: Xp22.2
USP9X Gene Summary
This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitin Specific Peptidase 9, X-linked
Chromosome: CHRX: 40944887 -41095832
Locus: Xp11.4
Gene Diseases
The USP9X RBBP7 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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