USP6NL-UPF2 Fusion FISH Probe
The USP6NL-UPF2 Fusion FISH Probe is used to confirm a fusion of the USP6NL and UPF2 genes. The fusion of the USP6NL and UPF2 genes has been associated with Stomach Adenocarcinoma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP6NL-UPF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-RERE | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-REOR | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-REGO | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-REGR | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-REAQ | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-ORRE | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-OROR | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-ORGO | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-GORE | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-GOOR | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-GOGO | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-GOGR | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-GRRE | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-GROR | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-GRGO | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-GRGR | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-AQRE | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-AQOR | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-AQGO | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-AQGR | 20 (40 μL) | 200 μL |
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| USP6NL-UPF2-20-AQAQ | 20 (40 μL) | 200 μL |
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USP6NL Gene Summary
The USP6 N-terminal Like (USP6NL) gene is located on chr10 :11502508-11653679 at 10p14.
Gene Name: USP6 N-terminal Like
Chromosome: CHR10: 11502508 -11653679
Locus: 10p14
UPF2 Gene Summary
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq, Jul 2008]
Gene Name: UPF2, Regulator Of Nonsense Mediated MRNA Decay
Chromosome: CHR10: 11962021 -12085023
Locus: 10p14
Gene Diseases
The USP6NL UPF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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