USP54-PSMA6 Fusion FISH Probe
The USP54-PSMA6 Fusion FISH Probe is used to confirm a fusion of the USP54 and PSMA6 genes. The fusion of the USP54 and PSMA6 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP54-PSMA6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-RERE | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-REOR | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-REGO | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-REGR | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-REAQ | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-ORRE | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-OROR | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-ORGO | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-ORAQ | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-GORE | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-GOOR | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-GOGO | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-GOGR | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-GOAQ | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-GRRE | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-GROR | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-GRGO | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-GRGR | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-GRAQ | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-AQRE | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-AQOR | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-AQGO | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-AQGR | 20 (40 μL) | 200 μL |
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| USP54-PSMA6-20-AQAQ | 20 (40 μL) | 200 μL |
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PSMA6 Gene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013]
Gene Name: Proteasome Subunit Alpha 6
Chromosome: CHR14: 35761573 -35786682
Locus: 14q13.2
USP54 Gene Summary
The Ubiquitin Specific Peptidase 54 (USP54) gene is located on chr10 :75257295-75335433 at 10q22.2.
Gene Name: Ubiquitin Specific Peptidase 54
Chromosome: CHR10: 75257295 -75335433
Locus: 10q22.2
Gene Diseases
The USP54 PSMA6 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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