USP54-AP3M1 Fusion FISH Probe
The USP54-AP3M1 Fusion FISH Probe is used to confirm a fusion of the USP54 and AP3M1 genes. The fusion of the USP54 and AP3M1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP54-AP3M1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-RERE | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-REOR | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-REGO | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-REGR | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-REAQ | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-ORRE | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-OROR | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-ORGO | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-ORAQ | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-GORE | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-GOOR | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-GOGO | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-GOGR | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-GOAQ | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-GRRE | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-GROR | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-GRGO | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-GRGR | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-GRAQ | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-AQRE | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-AQOR | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-AQGO | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-AQGR | 20 (40 μL) | 200 μL |
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| USP54-AP3M1-20-AQAQ | 20 (40 μL) | 200 μL |
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AP3M1 Gene Summary
The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: Adaptor Related Protein Complex 3 Mu 1 Subunit
Chromosome: CHR10: 75880014 -75910826
Locus: 10q22.2
USP54 Gene Summary
The Ubiquitin Specific Peptidase 54 (USP54) gene is located on chr10 :75257295-75335433 at 10q22.2.
Gene Name: Ubiquitin Specific Peptidase 54
Chromosome: CHR10: 75257295 -75335433
Locus: 10q22.2
Gene Diseases
The USP54 AP3M1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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