USP48-KALRN Fusion FISH Probe
The USP48-KALRN Fusion FISH Probe is used to confirm a fusion of the USP48 and KALRN genes. The fusion of the USP48 and KALRN genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP48-KALRN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-RERE | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-REOR | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-REGO | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-REGR | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-REAQ | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-ORRE | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-OROR | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-ORGO | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-ORAQ | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-GORE | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-GOOR | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-GOGO | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-GOGR | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-GOAQ | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-GRRE | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-GROR | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-GRGO | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-GRGR | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-GRAQ | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-AQRE | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-AQOR | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-AQGO | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-AQGR | 20 (40 μL) | 200 μL |
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| USP48-KALRN-20-AQAQ | 20 (40 μL) | 200 μL |
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KALRN Gene Summary
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016]
Gene Name: Kalirin RhoGEF Kinase
Chromosome: CHR3: 123813557 -124440036
Locus: 3q21.1-q21.2
USP48 Gene Summary
This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitin Specific Peptidase 48
Chromosome: CHR1: 22004791 -22109688
Locus: 1p36.12
Gene Diseases
The USP48 KALRN Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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