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USP45-RIOK1 Fusion FISH Probe

The USP45-RIOK1 Fusion FISH Probe is used to confirm a fusion of the USP45 and RIOK1 genes. The fusion of the USP45 and RIOK1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
USP45-RIOK1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
USP45-RIOK1-20-RERE 20 (40 μL) 200 μL
USP45-RIOK1-20-REOR 20 (40 μL) 200 μL
USP45-RIOK1-20-REGO 20 (40 μL) 200 μL
USP45-RIOK1-20-REGR 20 (40 μL) 200 μL
USP45-RIOK1-20-REAQ 20 (40 μL) 200 μL
USP45-RIOK1-20-ORRE 20 (40 μL) 200 μL
USP45-RIOK1-20-OROR 20 (40 μL) 200 μL
USP45-RIOK1-20-ORGO 20 (40 μL) 200 μL
USP45-RIOK1-20-ORAQ 20 (40 μL) 200 μL
USP45-RIOK1-20-GORE 20 (40 μL) 200 μL
USP45-RIOK1-20-GOOR 20 (40 μL) 200 μL
USP45-RIOK1-20-GOGO 20 (40 μL) 200 μL
USP45-RIOK1-20-GOGR 20 (40 μL) 200 μL
USP45-RIOK1-20-GOAQ 20 (40 μL) 200 μL
USP45-RIOK1-20-GRRE 20 (40 μL) 200 μL
USP45-RIOK1-20-GROR 20 (40 μL) 200 μL
USP45-RIOK1-20-GRGO 20 (40 μL) 200 μL
USP45-RIOK1-20-GRGR 20 (40 μL) 200 μL
USP45-RIOK1-20-GRAQ 20 (40 μL) 200 μL
USP45-RIOK1-20-AQRE 20 (40 μL) 200 μL
USP45-RIOK1-20-AQOR 20 (40 μL) 200 μL
USP45-RIOK1-20-AQGO 20 (40 μL) 200 μL
USP45-RIOK1-20-AQGR 20 (40 μL) 200 μL
USP45-RIOK1-20-AQAQ 20 (40 μL) 200 μL

RIOK1 Gene Summary

The protein encoded by this gene competes with pICln for inclusion in the protein arginine methyltransferase 5 complex. This complex targets substrates for dimethylation. The encoded protein is essential for the last steps in the maturation of 40S subunits. [provided by RefSeq, Jan 2017]

Gene Name: RIO Kinase 1

Chromosome: CHR6: 7390061 -7418270

Locus: 6p24.3

USP45 Gene Summary

The protein encoded by this gene is a deubiquitylase that binds ERCC1, the catalytic subunit of the XPF-ERCC1 DNA repair endonuclease. This endonuclease is a critical regulator of DNA repair processes, and the deubiquitylase activity of the encoded protein is important for maintaining the DNA repair ability of XPF-ERCC1. [provided by RefSeq, Sep 2016]

Gene Name: Ubiquitin Specific Peptidase 45

Chromosome: CHR6: 99880183 -99963252

Locus: 6q16.2

Gene Diseases

The USP45 RIOK1 Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.