USP4-SCRIB Fusion FISH Probe
The USP4-SCRIB Fusion FISH Probe is used to confirm a fusion of the USP4 and SCRIB genes. The fusion of the USP4 and SCRIB genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP4-SCRIB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-RERE | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-REOR | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-REGO | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-REGR | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-REAQ | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-ORRE | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-OROR | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-ORGO | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-ORAQ | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-GORE | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-GOOR | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-GOGO | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-GOGR | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-GOAQ | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-GRRE | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-GROR | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-GRGO | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-GRGR | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-GRAQ | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-AQRE | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-AQOR | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-AQGO | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-AQGR | 20 (40 μL) | 200 μL |
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| USP4-SCRIB-20-AQAQ | 20 (40 μL) | 200 μL |
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USP4 Gene Summary
The protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Ubiquitin Specific Peptidase 4
Chromosome: CHR3: 49314576 -49377536
Locus: 3p21.31
SCRIB Gene Summary
This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Name: Scribbled Planar Cell Polarity Protein
Chromosome: CHR8: 144873089 -144897549
Locus: 8q24.3
Gene Diseases
The USP4 SCRIB Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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