USP4-BBOX1 Fusion FISH Probe
The USP4-BBOX1 Fusion FISH Probe is used to confirm a fusion of the USP4 and BBOX1 genes. The fusion of the USP4 and BBOX1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP4-BBOX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-RERE | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-REOR | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-REGO | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-REGR | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-REAQ | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-ORRE | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-OROR | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-ORGO | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-GORE | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-GOOR | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-GOGO | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-GOGR | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-GRRE | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-GROR | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-GRGO | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-GRGR | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-AQRE | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-AQOR | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-AQGO | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-AQGR | 20 (40 μL) | 200 μL |
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| USP4-BBOX1-20-AQAQ | 20 (40 μL) | 200 μL |
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USP4 Gene Summary
The protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Ubiquitin Specific Peptidase 4
Chromosome: CHR3: 49314576 -49377536
Locus: 3p21.31
BBOX1 Gene Summary
This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation. [provided by RefSeq, Jul 2008]
Gene Name: Gamma-butyrobetaine Hydroxylase 1
Chromosome: CHR11: 27062508 -27149354
Locus: 11p14.2
Gene Diseases
The USP4 BBOX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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