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USP39-GGCX Fusion FISH Probe

The USP39-GGCX Fusion FISH Probe is used to confirm a fusion of the USP39 and GGCX genes. The fusion of the USP39 and GGCX genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
USP39-GGCX-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
USP39-GGCX-20-RERE 20 (40 μL) 200 μL
USP39-GGCX-20-REOR 20 (40 μL) 200 μL
USP39-GGCX-20-REGO 20 (40 μL) 200 μL
USP39-GGCX-20-REGR 20 (40 μL) 200 μL
USP39-GGCX-20-REAQ 20 (40 μL) 200 μL
USP39-GGCX-20-ORRE 20 (40 μL) 200 μL
USP39-GGCX-20-OROR 20 (40 μL) 200 μL
USP39-GGCX-20-ORGO 20 (40 μL) 200 μL
USP39-GGCX-20-ORAQ 20 (40 μL) 200 μL
USP39-GGCX-20-GORE 20 (40 μL) 200 μL
USP39-GGCX-20-GOOR 20 (40 μL) 200 μL
USP39-GGCX-20-GOGO 20 (40 μL) 200 μL
USP39-GGCX-20-GOGR 20 (40 μL) 200 μL
USP39-GGCX-20-GOAQ 20 (40 μL) 200 μL
USP39-GGCX-20-GRRE 20 (40 μL) 200 μL
USP39-GGCX-20-GROR 20 (40 μL) 200 μL
USP39-GGCX-20-GRGO 20 (40 μL) 200 μL
USP39-GGCX-20-GRGR 20 (40 μL) 200 μL
USP39-GGCX-20-GRAQ 20 (40 μL) 200 μL
USP39-GGCX-20-AQRE 20 (40 μL) 200 μL
USP39-GGCX-20-AQOR 20 (40 μL) 200 μL
USP39-GGCX-20-AQGO 20 (40 μL) 200 μL
USP39-GGCX-20-AQGR 20 (40 μL) 200 μL
USP39-GGCX-20-AQAQ 20 (40 μL) 200 μL

GGCX Gene Summary

This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Gene Name: Gamma-glutamyl Carboxylase

Chromosome: CHR2: 85771977 -85788657

Locus: 2p11.2

USP39 Gene Summary

The Ubiquitin Specific Peptidase 39 (USP39) gene is located on chr2 :85843282-85876406 at 2p11.2.

Gene Name: Ubiquitin Specific Peptidase 39

Chromosome: CHR2: 85843282 -85876406

Locus: 2p11.2

Gene Diseases

The USP39 GGCX Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.