USP39-GGCX Fusion FISH Probe
The USP39-GGCX Fusion FISH Probe is used to confirm a fusion of the USP39 and GGCX genes. The fusion of the USP39 and GGCX genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP39-GGCX-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-RERE | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-REOR | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-REGO | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-REGR | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-REAQ | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-ORRE | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-OROR | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-ORGO | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-ORAQ | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-GORE | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-GOOR | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-GOGO | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-GOGR | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-GOAQ | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-GRRE | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-GROR | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-GRGO | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-GRGR | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-GRAQ | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-AQRE | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-AQOR | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-AQGO | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-AQGR | 20 (40 μL) | 200 μL |
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| USP39-GGCX-20-AQAQ | 20 (40 μL) | 200 μL |
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GGCX Gene Summary
This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Gene Name: Gamma-glutamyl Carboxylase
Chromosome: CHR2: 85771977 -85788657
Locus: 2p11.2
USP39 Gene Summary
The Ubiquitin Specific Peptidase 39 (USP39) gene is located on chr2 :85843282-85876406 at 2p11.2.
Gene Name: Ubiquitin Specific Peptidase 39
Chromosome: CHR2: 85843282 -85876406
Locus: 2p11.2
Gene Diseases
The USP39 GGCX Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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