USP39-CD8B Fusion FISH Probe
The USP39-CD8B Fusion FISH Probe is used to confirm a fusion of the USP39 and CD8B genes. The fusion of the USP39 and CD8B genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP39-CD8B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-RERE | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-REOR | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-REGO | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-REGR | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-REAQ | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-ORRE | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-OROR | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-ORGO | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-ORAQ | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-GORE | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-GOOR | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-GOGO | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-GOGR | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-GOAQ | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-GRRE | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-GROR | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-GRGO | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-GRGR | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-GRAQ | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-AQRE | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-AQOR | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-AQGO | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-AQGR | 20 (40 μL) | 200 μL |
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| USP39-CD8B-20-AQAQ | 20 (40 μL) | 200 μL |
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CD8B Gene Summary
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
Gene Name: CD8b Molecule
Chromosome: CHR2: 87042459 -87089047
Locus: 2p11.2
USP39 Gene Summary
The Ubiquitin Specific Peptidase 39 (USP39) gene is located on chr2 :85843282-85876406 at 2p11.2.
Gene Name: Ubiquitin Specific Peptidase 39
Chromosome: CHR2: 85843282 -85876406
Locus: 2p11.2
Gene Diseases
The USP39 CD8B Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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