USP35-TSHZ2 Fusion FISH Probe
The USP35-TSHZ2 Fusion FISH Probe is used to confirm a fusion of the USP35 and TSHZ2 genes. The fusion of the USP35 and TSHZ2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP35-TSHZ2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-RERE | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-REOR | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-REGO | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-REGR | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-REAQ | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-ORRE | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-OROR | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-ORGO | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-ORAQ | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-GORE | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-GOOR | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-GOGO | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-GOGR | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-GOAQ | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-GRRE | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-GROR | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-GRGO | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-GRGR | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-GRAQ | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-AQRE | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-AQOR | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-AQGO | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-AQGR | 20 (40 μL) | 200 μL |
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| USP35-TSHZ2-20-AQAQ | 20 (40 μL) | 200 μL |
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USP35 Gene Summary
This gene encodes a member of the peptidase C19 family of ubiquitin-specific proteases. These deubiquitinating enzymes (DUBs) catalyze the removal of ubiquitin proteins from other proteins. The encoded protein associates with polarized mitochondria and has been shown to inhibit NF-kappa B activation and delay PARK2-mediated degradation of mitochondria. Expression of this gene is upregulated by the let-7a microRNA and reduced expression has been observed in human tumor tissues. [provided by RefSeq, Jul 2017]
Gene Name: Ubiquitin Specific Peptidase 35
Chromosome: CHR11: 77899857 -77925757
Locus: 11q14.1
TSHZ2 Gene Summary
This gene is a member of the teashirt C2H2-type zinc-finger protein family of transcription factors. This gene encodes a protein with five C2H2-type zinc fingers, a homeobox DNA-binding domain and a coiled-coil domain. This nuclear protein is predicted to act as a transcriptional repressor. This gene is thought to play a role in the development and progression of breast and other types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Gene Name: Teashirt Zinc Finger Homeobox 2
Chromosome: CHR20: 51588945 -52111869
Locus: 20q13.2
Gene Diseases
The USP35 TSHZ2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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