USP13-KCNMB2 Fusion FISH Probe
The USP13-KCNMB2 Fusion FISH Probe is used to confirm a fusion of the USP13 and KCNMB2 genes. The fusion of the USP13 and KCNMB2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP13-KCNMB2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-RERE | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-REOR | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-REGO | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-REGR | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-REAQ | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-ORRE | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-OROR | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-ORGO | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-ORAQ | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-GORE | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-GOOR | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-GOGO | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-GOGR | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-GOAQ | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-GRRE | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-GROR | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-GRGO | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-GRGR | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-GRAQ | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-AQRE | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-AQOR | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-AQGO | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-AQGR | 20 (40 μL) | 200 μL |
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| USP13-KCNMB2-20-AQAQ | 20 (40 μL) | 200 μL |
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USP13 Gene Summary
The Ubiquitin Specific Peptidase 13 (USP13) gene is located on chr3 :179370932-179507189 at 3q26.33.
Gene Name: Ubiquitin Specific Peptidase 13
Chromosome: CHR3: 179370932 -179507189
Locus: 3q26.33
KCNMB2 Gene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described. [provided by RefSeq, Jul 2013]
Gene Name: Potassium Calcium-activated Channel Subfamily M Regulatory Beta Subunit 2
Chromosome: CHR3: 178254223 -178562217
Locus: 3q26.32
Gene Diseases
The USP13 KCNMB2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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