URM1-TP53BP1 Fusion FISH Probe
The URM1-TP53BP1 Fusion FISH Probe is used to confirm a fusion of the URM1 and TP53BP1 genes. The fusion of the URM1 and TP53BP1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| URM1-TP53BP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-RERE | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-REOR | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-REGO | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-REGR | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-REAQ | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-ORRE | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-OROR | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-ORGO | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-GORE | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-GOOR | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-GOGO | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-GOGR | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-GRRE | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-GROR | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-GRGO | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-GRGR | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-AQRE | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-AQOR | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-AQGO | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-AQGR | 20 (40 μL) | 200 μL |
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| URM1-TP53BP1-20-AQAQ | 20 (40 μL) | 200 μL |
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TP53BP1 Gene Summary
This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
Gene Name: Tumor Protein P53 Binding Protein 1
Chromosome: CHR15: 43699411 -43802707
Locus: 15q15.3
URM1 Gene Summary
The Ubiquitin Related Modifier 1 (URM1) gene is located on chr9 :131133597-131153015 at 9q34.11.
Gene Name: Ubiquitin Related Modifier 1
Chromosome: CHR9: 131133597 -131153015
Locus: 9q34.11
Gene Diseases
The URM1 TP53BP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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