UQCRC1-FNIP2 Fusion FISH Probe
The UQCRC1-FNIP2 Fusion FISH Probe is used to confirm a fusion of the UQCRC1 and FNIP2 genes. The fusion of the UQCRC1 and FNIP2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UQCRC1-FNIP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-RERE | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-REOR | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-REGO | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-REGR | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-REAQ | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-ORRE | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-OROR | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-ORGO | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-GORE | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-GOOR | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-GOGO | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-GOGR | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-GRRE | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-GROR | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-GRGO | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-GRGR | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-AQRE | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-AQOR | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-AQGO | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-AQGR | 20 (40 μL) | 200 μL |
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| UQCRC1-FNIP2-20-AQAQ | 20 (40 μL) | 200 μL |
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UQCRC1 Gene Summary
The Ubiquinol-cytochrome C Reductase Core Protein 1 (UQCRC1) gene is located on chr3 :48636431-48647098 at 3p21.31.
Gene Name: Ubiquinol-cytochrome C Reductase Core Protein 1
Chromosome: CHR3: 48636431 -48647098
Locus: 3p21.31
FNIP2 Gene Summary
This gene encodes a protein that binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK), and may play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. The encoded protein may also be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017]
Gene Name: Folliculin Interacting Protein 2
Chromosome: CHR4: 159690181 -159827954
Locus: 4q32.1
Gene Diseases
The UQCRC1 FNIP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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