UQCC-GDF5 Fusion FISH Probe
The UQCC-GDF5 Fusion FISH Probe is used to confirm a fusion of the UQCC and GDF5 genes. The fusion of the UQCC and GDF5 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UQCC-GDF5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-RERE | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-REOR | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-REGO | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-REGR | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-REAQ | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-ORRE | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-OROR | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-ORGO | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-ORAQ | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-GORE | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-GOOR | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-GOGO | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-GOGR | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-GOAQ | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-GRRE | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-GROR | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-GRGO | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-GRGR | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-GRAQ | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-AQRE | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-AQOR | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-AQGO | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-AQGR | 20 (40 μL) | 200 μL |
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| UQCC-GDF5-20-AQAQ | 20 (40 μL) | 200 μL |
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GDF5 Gene Summary
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis. [provided by RefSeq, Aug 2016]
Gene Name: Growth Differentiation Factor 5
Chromosome: CHR20: 34021148 -34026027
Locus: 20q11.22
Gene Diseases
The UQCC GDF5 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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