UPP1-NCALD Fusion FISH Probe
The UPP1-NCALD Fusion FISH Probe is used to confirm a fusion of the UPP1 and NCALD genes. The fusion of the UPP1 and NCALD genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UPP1-NCALD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-RERE | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-REOR | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-REGO | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-REGR | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-REAQ | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-ORRE | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-OROR | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-ORGO | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-ORAQ | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-GORE | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-GOOR | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-GOGO | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-GOGR | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-GOAQ | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-GRRE | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-GROR | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-GRGO | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-GRGR | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-GRAQ | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-AQRE | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-AQOR | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-AQGO | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-AQGR | 20 (40 μL) | 200 μL |
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| UPP1-NCALD-20-AQAQ | 20 (40 μL) | 200 μL |
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UPP1 Gene Summary
This gene encodes a uridine phosphorylase, an enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded enzyme functions in the degradation and salvage of pyrimidine ribonucleosides. [provided by RefSeq, Oct 2016]
Gene Name: Uridine Phosphorylase 1
Chromosome: CHR7: 48128354 -48148330
Locus: 7p12.3
NCALD Gene Summary
This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Neurocalcin Delta
Chromosome: CHR8: 102698769 -103137135
Locus: 8q22.3
Gene Diseases
The UPP1 NCALD Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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