UNKL-DIP2B Fusion FISH Probe
The UNKL-DIP2B Fusion FISH Probe is used to confirm a fusion of the UNKL and DIP2B genes. The fusion of the UNKL and DIP2B genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UNKL-DIP2B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-RERE | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-REOR | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-REGO | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-REGR | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-REAQ | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-ORRE | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-OROR | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-ORGO | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-ORAQ | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-GORE | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-GOOR | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-GOGO | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-GOGR | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-GOAQ | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-GRRE | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-GROR | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-GRGO | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-GRGR | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-GRAQ | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-AQRE | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-AQOR | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-AQGO | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-AQGR | 20 (40 μL) | 200 μL |
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| UNKL-DIP2B-20-AQAQ | 20 (40 μL) | 200 μL |
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DIP2B Gene Summary
This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12. [provided by RefSeq, Aug 2011]
Gene Name: Disco Interacting Protein 2 Homolog B
Chromosome: CHR12: 50898767 -51142450
Locus: 12q13.12
UNKL Gene Summary
This gene encodes a RING finger protein that may function in Rac signaling. It can bind to Brg/Brm-associated factor 60b and can promote its ubiquitination. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Gene Name: Unkempt Family Like Zinc Finger
Chromosome: CHR16: 1413205 -1464705
Locus: 16p13.3
Gene Diseases
The UNKL DIP2B Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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