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UNK-DPYD Fusion FISH Probe

The UNK-DPYD Fusion FISH Probe is used to confirm a fusion of the UNK and DPYD genes. The fusion of the UNK and DPYD genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
UNK-DPYD-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
UNK-DPYD-20-RERE 20 (40 μL) 200 μL
UNK-DPYD-20-REOR 20 (40 μL) 200 μL
UNK-DPYD-20-REGO 20 (40 μL) 200 μL
UNK-DPYD-20-REGR 20 (40 μL) 200 μL
UNK-DPYD-20-REAQ 20 (40 μL) 200 μL
UNK-DPYD-20-ORRE 20 (40 μL) 200 μL
UNK-DPYD-20-OROR 20 (40 μL) 200 μL
UNK-DPYD-20-ORGO 20 (40 μL) 200 μL
UNK-DPYD-20-ORAQ 20 (40 μL) 200 μL
UNK-DPYD-20-GORE 20 (40 μL) 200 μL
UNK-DPYD-20-GOOR 20 (40 μL) 200 μL
UNK-DPYD-20-GOGO 20 (40 μL) 200 μL
UNK-DPYD-20-GOGR 20 (40 μL) 200 μL
UNK-DPYD-20-GOAQ 20 (40 μL) 200 μL
UNK-DPYD-20-GRRE 20 (40 μL) 200 μL
UNK-DPYD-20-GROR 20 (40 μL) 200 μL
UNK-DPYD-20-GRGO 20 (40 μL) 200 μL
UNK-DPYD-20-GRGR 20 (40 μL) 200 μL
UNK-DPYD-20-GRAQ 20 (40 μL) 200 μL
UNK-DPYD-20-AQRE 20 (40 μL) 200 μL
UNK-DPYD-20-AQOR 20 (40 μL) 200 μL
UNK-DPYD-20-AQGO 20 (40 μL) 200 μL
UNK-DPYD-20-AQGR 20 (40 μL) 200 μL
UNK-DPYD-20-AQAQ 20 (40 μL) 200 μL

DPYD Gene Summary

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Gene Name: Dihydropyrimidine Dehydrogenase

Chromosome: CHR1: 97543299 -98386615

Locus: 1p21.3

UNK Gene Summary

The Unkempt Family Zinc Finger (UNK) gene is located on chr17 :73780919-73821886 at 17q25.1.

Gene Name: Unkempt Family Zinc Finger

Chromosome: CHR17: 73780919 -73821886

Locus: 17q25.1

Gene Diseases

The UNK DPYD Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.