UNC13D-FBF1 Fusion FISH Probe
The UNC13D-FBF1 Fusion FISH Probe is used to confirm a fusion of the UNC13D and FBF1 genes. The fusion of the UNC13D and FBF1 genes has been associated with Lung Squamous Cell Carcinoma, and Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UNC13D-FBF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-RERE | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-REOR | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-REGO | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-REGR | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-REAQ | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-ORRE | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-OROR | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-ORGO | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-GORE | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-GOOR | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-GOGO | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-GOGR | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-GRRE | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-GROR | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-GRGO | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-GRGR | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-AQRE | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-AQOR | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-AQGO | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-AQGR | 20 (40 μL) | 200 μL |
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| UNC13D-FBF1-20-AQAQ | 20 (40 μL) | 200 μL |
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FBF1 Gene Summary
The Fas Binding Factor 1 (FBF1) gene is located on chr17 :73906617-73937119 at 17q25.1.
Gene Name: Fas Binding Factor 1
Chromosome: CHR17: 73906617 -73937119
Locus: 17q25.1
UNC13D Gene Summary
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]
Gene Name: Unc-13 Homolog D
Chromosome: CHR17: 73823307 -73840798
Locus: 17q25.1
Gene Diseases
The UNC13D FBF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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