UNC13B-TAF7L Fusion FISH Probe
The UNC13B-TAF7L Fusion FISH Probe is used to confirm a fusion of the UNC13B and TAF7L genes. The fusion of the UNC13B and TAF7L genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UNC13B-TAF7L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-RERE | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-REOR | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-REGO | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-REGR | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-REAQ | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-ORRE | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-OROR | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-ORGO | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-ORAQ | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-GORE | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-GOOR | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-GOGO | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-GOGR | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-GOAQ | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-GRRE | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-GROR | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-GRGO | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-GRGR | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-GRAQ | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-AQRE | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-AQOR | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-AQGO | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-AQGR | 20 (40 μL) | 200 μL |
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| UNC13B-TAF7L-20-AQAQ | 20 (40 μL) | 200 μL |
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UNC13B Gene Summary
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008]
Gene Name: Unc-13 Homolog B
Chromosome: CHR9: 35161988 -35405332
Locus: 9p13.3
TAF7L Gene Summary
This gene is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Gene Name: TATA-box Binding Protein Associated Factor 7 Like
Chromosome: CHRX: 100523240 -100548059
Locus: Xq22.1
Gene Diseases
The UNC13B TAF7L Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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