UNC13B-SLMO1 Fusion FISH Probe
The UNC13B-SLMO1 Fusion FISH Probe is used to confirm a fusion of the UNC13B and SLMO1 genes. The fusion of the UNC13B and SLMO1 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UNC13B-SLMO1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-RERE | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-REOR | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-REGO | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-REGR | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-REAQ | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-ORRE | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-OROR | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-ORGO | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-ORAQ | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-GORE | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-GOOR | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-GOGO | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-GOGR | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-GOAQ | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-GRRE | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-GROR | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-GRGO | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-GRGR | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-GRAQ | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-AQRE | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-AQOR | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-AQGO | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-AQGR | 20 (40 μL) | 200 μL |
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| UNC13B-SLMO1-20-AQAQ | 20 (40 μL) | 200 μL |
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UNC13B Gene Summary
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008]
Gene Name: Unc-13 Homolog B
Chromosome: CHR9: 35161988 -35405332
Locus: 9p13.3
Gene Diseases
The UNC13B SLMO1 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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