ULK4-FBXO44 Fusion FISH Probe
The ULK4-FBXO44 Fusion FISH Probe is used to confirm a fusion of the ULK4 and FBXO44 genes. The fusion of the ULK4 and FBXO44 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ULK4-FBXO44-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-RERE | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-REOR | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-REGO | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-REGR | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-REAQ | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-ORRE | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-OROR | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-ORGO | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-ORAQ | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-GORE | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-GOOR | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-GOGO | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-GOGR | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-GOAQ | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-GRRE | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-GROR | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-GRGO | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-GRGR | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-GRAQ | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-AQRE | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-AQOR | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-AQGO | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-AQGR | 20 (40 μL) | 200 μL |
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| ULK4-FBXO44-20-AQAQ | 20 (40 μL) | 200 μL |
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ULK4 Gene Summary
This gene encodes a member of the unc-51-like serine/threonine kinase (STK) family. Members of this protein family play a role in neuronal growth and endocytosis. The encoded protein is likely involved in neurite branching, neurite elongation and neuronal migration. Genome-wide association studies (GWAS) indicate an association of variations in this gene with blood pressure and hypertension. Sequence variations in this gene may also be be associated with psychiatric disorders, including schizophrenia and bipolar disorder. Pseudogenes associated with this gene have been identified and are located on chromosome 15. [provided by RefSeq, Jul 2016]
Gene Name: Unc-51 Like Kinase 4
Chromosome: CHR3: 41288089 -42003660
Locus: 3p22.1
FBXO44 Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Several alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Feb 2015]
Gene Name: F-box Protein 44
Chromosome: CHR1: 11714431 -11723384
Locus: 1p36.22
Gene Diseases
The ULK4 FBXO44 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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