ULK2-MBD3 Fusion FISH Probe
The ULK2-MBD3 Fusion FISH Probe is used to confirm a fusion of the ULK2 and MBD3 genes. The fusion of the ULK2 and MBD3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ULK2-MBD3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ULK2-MBD3-20-AQAQ | 20 (40 μL) | 200 μL |
|
ULK2 Gene Summary
This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008]
Gene Name: Unc-51 Like Autophagy Activating Kinase 2
Chromosome: CHR17: 19674142 -19771239
Locus: 17p11.2
MBD3 Gene Summary
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Gene Name: Methyl-CpG Binding Domain Protein 3
Chromosome: CHR19: 1576677 -1592652
Locus: 19p13.3
Gene Diseases
The ULK2 MBD3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|