ULK2-DOCK6 Fusion FISH Probe
The ULK2-DOCK6 Fusion FISH Probe is used to confirm a fusion of the ULK2 and DOCK6 genes. The fusion of the ULK2 and DOCK6 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ULK2-DOCK6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-RERE | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-REOR | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-REGO | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-REGR | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-REAQ | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-ORRE | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-OROR | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-ORGO | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-ORAQ | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-GORE | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-GOOR | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-GOGO | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-GOGR | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-GOAQ | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-GRRE | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-GROR | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-GRGO | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-GRGR | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-GRAQ | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-AQRE | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-AQOR | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-AQGO | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-AQGR | 20 (40 μL) | 200 μL |
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| ULK2-DOCK6-20-AQAQ | 20 (40 μL) | 200 μL |
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ULK2 Gene Summary
This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008]
Gene Name: Unc-51 Like Autophagy Activating Kinase 2
Chromosome: CHR17: 19674142 -19771239
Locus: 17p11.2
DOCK6 Gene Summary
This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2. [provided by RefSeq, Dec 2011]
Gene Name: Dedicator Of Cytokinesis 6
Chromosome: CHR19: 11309970 -11373157
Locus: 19p13.2
Gene Diseases
The ULK2 DOCK6 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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