UGP2-PLEKHM3 Fusion FISH Probe
The UGP2-PLEKHM3 Fusion FISH Probe is used to confirm a fusion of the UGP2 and PLEKHM3 genes. The fusion of the UGP2 and PLEKHM3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UGP2-PLEKHM3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-RERE | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-REOR | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-REGO | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-REGR | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-REAQ | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-ORRE | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-OROR | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-ORGO | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-ORAQ | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-GORE | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-GOOR | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-GOGO | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-GOGR | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-GOAQ | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-GRRE | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-GROR | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-GRGO | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-GRGR | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-GRAQ | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-AQRE | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-AQOR | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-AQGO | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-AQGR | 20 (40 μL) | 200 μL |
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| UGP2-PLEKHM3-20-AQAQ | 20 (40 μL) | 200 μL |
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UGP2 Gene Summary
The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: UDP-glucose Pyrophosphorylase 2
Chromosome: CHR2: 64068097 -64118696
Locus: 2p15
PLEKHM3 Gene Summary
The Pleckstrin Homology Domain Containing M3 (PLEKHM3) gene is located on chr2 :208686011-208890284 at 2q33.3.
Gene Name: Pleckstrin Homology Domain Containing M3
Chromosome: CHR2: 208686011 -208890284
Locus: 2q33.3
Gene Diseases
The UGP2 PLEKHM3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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