UCK2-TBX19 Fusion FISH Probe
The UCK2-TBX19 Fusion FISH Probe is used to confirm a fusion of the UCK2 and TBX19 genes. The fusion of the UCK2 and TBX19 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UCK2-TBX19-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-RERE | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-REOR | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-REGO | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-REGR | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-REAQ | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-ORRE | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-OROR | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-ORGO | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-ORAQ | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-GORE | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-GOOR | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-GOGO | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-GOGR | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-GOAQ | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-GRRE | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-GROR | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-GRGO | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-GRGR | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-GRAQ | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-AQRE | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-AQOR | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-AQGO | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-AQGR | 20 (40 μL) | 200 μL |
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| UCK2-TBX19-20-AQAQ | 20 (40 μL) | 200 μL |
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UCK2 Gene Summary
This gene encodes a pyrimidine ribonucleoside kinase. The encoded protein (EC 2.7.1.48) catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively.[provided by RefSeq, Oct 2010]
Gene Name: Uridine-cytidine Kinase 2
Chromosome: CHR1: 165796731 -165880855
Locus: 1q24.1
TBX19 Gene Summary
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. [provided by RefSeq, Jul 2008]
Gene Name: T-box 19
Chromosome: CHR1: 168250277 -168283664
Locus: 1q24.2
Gene Diseases
The UCK2 TBX19 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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