UBTF-CA10 Fusion FISH Probe
The UBTF-CA10 Fusion FISH Probe is used to confirm a fusion of the UBTF and CA10 genes. The fusion of the UBTF and CA10 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBTF-CA10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-RERE | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-REOR | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-REGO | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-REGR | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-REAQ | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-ORRE | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-OROR | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-ORGO | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-GORE | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-GOOR | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-GOGO | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-GOGR | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-GRRE | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-GROR | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-GRGO | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-GRGR | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-AQRE | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-AQOR | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-AQGO | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-AQGR | 20 (40 μL) | 200 μL |
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| UBTF-CA10-20-AQAQ | 20 (40 μL) | 200 μL |
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UBTF Gene Summary
This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]
Gene Name: Upstream Binding Transcription Factor, RNA Polymerase I
Chromosome: CHR17: 42282400 -42298994
Locus: 17q21.31
CA10 Gene Summary
This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Carbonic Anhydrase 10
Chromosome: CHR17: 49707673 -50237377
Locus: 17q21.33-q22
Gene Diseases
The UBTF CA10 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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