UBR5-RIMS4 Fusion FISH Probe
The UBR5-RIMS4 Fusion FISH Probe is used to confirm a fusion of the UBR5 and RIMS4 genes. The fusion of the UBR5 and RIMS4 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBR5-RIMS4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-RERE | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-REOR | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-REGO | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-REGR | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-REAQ | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-ORRE | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-OROR | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-ORGO | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-GORE | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-GOOR | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-GOGO | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-GOGR | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-GRRE | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-GROR | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-GRGO | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-GRGR | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-AQRE | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-AQOR | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-AQGO | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-AQGR | 20 (40 μL) | 200 μL |
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| UBR5-RIMS4-20-AQAQ | 20 (40 μL) | 200 μL |
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UBR5 Gene Summary
This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitin Protein Ligase E3 Component N-recognin 5
Chromosome: CHR8: 103264501 -103424917
Locus: 8q22.3
RIMS4 Gene Summary
The Regulating Synaptic Membrane Exocytosis 4 (RIMS4) gene is located on chr20 :43380444-43438979 at 20q13.12.
Gene Name: Regulating Synaptic Membrane Exocytosis 4
Chromosome: CHR20: 43380444 -43438979
Locus: 20q13.12
Gene Diseases
The UBR5 RIMS4 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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