UBR5-ODF1 Fusion FISH Probe
The UBR5-ODF1 Fusion FISH Probe is used to confirm a fusion of the UBR5 and ODF1 genes. The fusion of the UBR5 and ODF1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBR5-ODF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-RERE | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-REOR | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-REGO | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-REGR | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-REAQ | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-ORRE | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-OROR | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-ORGO | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-GORE | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-GOOR | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-GOGO | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-GOGR | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-GRRE | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-GROR | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-GRGO | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-GRGR | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-AQRE | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-AQOR | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-AQGO | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-AQGR | 20 (40 μL) | 200 μL |
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| UBR5-ODF1-20-AQAQ | 20 (40 μL) | 200 μL |
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ODF1 Gene Summary
The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. The human outer dense fibers contains at least 10 major proteins and this gene encodes the main protein. [provided by RefSeq, Jul 2008]
Gene Name: Outer Dense Fiber Of Sperm Tails 1
Chromosome: CHR8: 103563847 -103573245
Locus: 8q22.3
UBR5 Gene Summary
This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitin Protein Ligase E3 Component N-recognin 5
Chromosome: CHR8: 103264501 -103424917
Locus: 8q22.3
Gene Diseases
The UBR5 ODF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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