UBR2-PXT1 Fusion FISH Probe
The UBR2-PXT1 Fusion FISH Probe is used to confirm a fusion of the UBR2 and PXT1 genes. The fusion of the UBR2 and PXT1 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBR2-PXT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-RERE | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-REOR | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-REGO | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-REGR | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-REAQ | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-ORRE | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-OROR | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-ORGO | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-GORE | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-GOOR | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-GOGO | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-GOGR | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-GRRE | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-GROR | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-GRGO | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-GRGR | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-AQRE | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-AQOR | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-AQGO | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-AQGR | 20 (40 μL) | 200 μL |
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| UBR2-PXT1-20-AQAQ | 20 (40 μL) | 200 μL |
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UBR2 Gene Summary
This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: Ubiquitin Protein Ligase E3 Component N-recognin 2
Chromosome: CHR6: 42531759 -42661243
Locus: 6p21.1
PXT1 Gene Summary
The Peroxisomal, Testis Specific 1 (PXT1) gene is located on chr6 :36358328-36410666 at 6p21.31.
Gene Name: Peroxisomal, Testis Specific 1
Chromosome: CHR6: 36358328 -36410666
Locus: 6p21.31
Gene Diseases
The UBR2 PXT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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