UBR2-MED20 Fusion FISH Probe
The UBR2-MED20 Fusion FISH Probe is used to confirm a fusion of the UBR2 and MED20 genes. The fusion of the UBR2 and MED20 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBR2-MED20-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-RERE | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-REOR | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-REGO | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-REGR | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-REAQ | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-ORRE | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-OROR | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-ORGO | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-GORE | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-GOOR | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-GOGO | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-GOGR | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-GRRE | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-GROR | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-GRGO | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-GRGR | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-AQRE | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-AQOR | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-AQGO | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-AQGR | 20 (40 μL) | 200 μL |
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| UBR2-MED20-20-AQAQ | 20 (40 μL) | 200 μL |
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MED20 Gene Summary
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. A mutation in this gene has been associated with a novel infantile-onset neurodegenerative movement disorder. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]
Gene Name: Mediator Complex Subunit 20
Chromosome: CHR6: 41873091 -41888877
Locus: 6p21.1
UBR2 Gene Summary
This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: Ubiquitin Protein Ligase E3 Component N-recognin 2
Chromosome: CHR6: 42531759 -42661243
Locus: 6p21.1
Gene Diseases
The UBR2 MED20 Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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