UBR2-KANK2 Fusion FISH Probe
The UBR2-KANK2 Fusion FISH Probe is used to confirm a fusion of the UBR2 and KANK2 genes. The fusion of the UBR2 and KANK2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBR2-KANK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-RERE | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-REOR | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-REGO | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-REGR | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-REAQ | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-ORRE | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-OROR | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-ORGO | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-GORE | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-GOOR | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-GOGO | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-GOGR | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-GRRE | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-GROR | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-GRGO | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-GRGR | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-AQRE | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-AQOR | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-AQGO | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-AQGR | 20 (40 μL) | 200 μL |
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| UBR2-KANK2-20-AQAQ | 20 (40 μL) | 200 μL |
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UBR2 Gene Summary
This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: Ubiquitin Protein Ligase E3 Component N-recognin 2
Chromosome: CHR6: 42531759 -42661243
Locus: 6p21.1
KANK2 Gene Summary
This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair. [provided by RefSeq, Jul 2016]
Gene Name: KN Motif And Ankyrin Repeat Domains 2
Chromosome: CHR19: 11274942 -11308243
Locus: 19p13.2
Gene Diseases
The UBR2 KANK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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