UBQLN1-NAV3 Fusion FISH Probe
The UBQLN1-NAV3 Fusion FISH Probe is used to confirm a fusion of the UBQLN1 and NAV3 genes. The fusion of the UBQLN1 and NAV3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBQLN1-NAV3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-RERE | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-REOR | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-REGO | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-REGR | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-REAQ | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-ORRE | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-OROR | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-ORGO | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-GORE | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-GOOR | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-GOGO | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-GOGR | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-GRRE | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-GROR | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-GRGO | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-GRGR | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-AQRE | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-AQOR | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-AQGO | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-AQGR | 20 (40 μL) | 200 μL |
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| UBQLN1-NAV3-20-AQAQ | 20 (40 μL) | 200 μL |
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UBQLN1 Gene Summary
This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquilin 1
Chromosome: CHR9: 86274877 -86323168
Locus: 9q21.2-q21.3
NAV3 Gene Summary
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined. [provided by RefSeq, Jul 2008]
Gene Name: Neuron Navigator 3
Chromosome: CHR12: 78225068 -78606790
Locus: 12q21.2
Gene Diseases
The UBQLN1 NAV3 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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