UBL3-SUCLA2 Fusion FISH Probe
The UBL3-SUCLA2 Fusion FISH Probe is used to confirm a fusion of the UBL3 and SUCLA2 genes. The fusion of the UBL3 and SUCLA2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBL3-SUCLA2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-RERE | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-REOR | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-REGO | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-REGR | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-REAQ | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-ORRE | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-OROR | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-ORGO | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-GORE | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-GOOR | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-GOGO | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-GOGR | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-GRRE | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-GROR | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-GRGO | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-GRGR | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-AQRE | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-AQOR | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-AQGO | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-AQGR | 20 (40 μL) | 200 μL |
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| UBL3-SUCLA2-20-AQAQ | 20 (40 μL) | 200 μL |
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UBL3 Gene Summary
The Ubiquitin Like 3 (UBL3) gene is located on chr13 :30338544-30424820 at 13q12.3.
Gene Name: Ubiquitin Like 3
Chromosome: CHR13: 30338544 -30424820
Locus: 13q12.3
SUCLA2 Gene Summary
Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq, Jul 2008]
Gene Name: Succinate-CoA Ligase ADP-forming Beta Subunit
Chromosome: CHR13: 48516790 -48575462
Locus: 13q14.2
Gene Diseases
The UBL3 SUCLA2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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