UBE2Q1-MYO7A Fusion FISH Probe
The UBE2Q1-MYO7A Fusion FISH Probe is used to confirm a fusion of the UBE2Q1 and MYO7A genes. The fusion of the UBE2Q1 and MYO7A genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBE2Q1-MYO7A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-RERE | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-REOR | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-REGO | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-REGR | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-REAQ | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-ORRE | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-OROR | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-ORGO | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-GORE | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-GOOR | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-GOGO | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-GOGR | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-GRRE | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-GROR | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-GRGO | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-GRGR | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-AQRE | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-AQOR | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-AQGO | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-AQGR | 20 (40 μL) | 200 μL |
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| UBE2Q1-MYO7A-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO7A Gene Summary
This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: Myosin VIIA
Chromosome: CHR11: 76839309 -76926286
Locus: 11q13.5
UBE2Q1 Gene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitin Conjugating Enzyme E2 Q1
Chromosome: CHR1: 154521050 -154531120
Locus: 1q21.3
Gene Diseases
The UBE2Q1 MYO7A Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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