UBE2F-RAMP1 Fusion FISH Probe
The UBE2F-RAMP1 Fusion FISH Probe is used to confirm a fusion of the UBE2F and RAMP1 genes. The fusion of the UBE2F and RAMP1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBE2F-RAMP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-RERE | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-REOR | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-REGO | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-REGR | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-REAQ | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-ORRE | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-OROR | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-ORGO | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-GORE | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-GOOR | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-GOGO | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-GOGR | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-GRRE | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-GROR | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-GRGO | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-GRGR | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-AQRE | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-AQOR | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-AQGO | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-AQGR | 20 (40 μL) | 200 μL |
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| UBE2F-RAMP1-20-AQAQ | 20 (40 μL) | 200 μL |
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RAMP1 Gene Summary
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Gene Name: Receptor Activity Modifying Protein 1
Chromosome: CHR2: 238768186 -238820755
Locus: 2q37.3
UBE2F Gene Summary
The Ubiquitin Conjugating Enzyme E2 F (putative) (UBE2F) gene is located on chr2 :238875586-238951423 at 2q37.3.
Gene Name: Ubiquitin Conjugating Enzyme E2 F (putative)
Chromosome: CHR2: 238875586 -238951423
Locus: 2q37.3
Gene Diseases
The UBE2F RAMP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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