UBE2E1-RAB14 Fusion FISH Probe
The UBE2E1-RAB14 Fusion FISH Probe is used to confirm a fusion of the UBE2E1 and RAB14 genes. The fusion of the UBE2E1 and RAB14 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBE2E1-RAB14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-RERE | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-REOR | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-REGO | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-REGR | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-REAQ | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-ORRE | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-OROR | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-ORGO | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-GORE | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-GOOR | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-GOGO | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-GOGR | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-GRRE | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-GROR | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-GRGO | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-GRGR | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-AQRE | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-AQOR | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-AQGO | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-AQGR | 20 (40 μL) | 200 μL |
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| UBE2E1-RAB14-20-AQAQ | 20 (40 μL) | 200 μL |
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UBE2E1 Gene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Gene Name: Ubiquitin Conjugating Enzyme E2 E1
Chromosome: CHR3: 23847383 -23933131
Locus: 3p24.2
RAB14 Gene Summary
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM, Mar 2009]
Gene Name: RAB14, Member RAS Oncogene Family
Chromosome: CHR9: 123940414 -123964365
Locus: 9q33.2
Gene Diseases
The UBE2E1 RAB14 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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