UBA6-CCNA2 Fusion FISH Probe
The UBA6-CCNA2 Fusion FISH Probe is used to confirm a fusion of the UBA6 and CCNA2 genes. The fusion of the UBA6 and CCNA2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBA6-CCNA2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-RERE | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-REOR | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-REGO | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-REGR | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-REAQ | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-ORRE | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-OROR | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-ORGO | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-GORE | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-GOOR | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-GOGO | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-GOGR | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-GRRE | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-GROR | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-GRGO | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-GRGR | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-AQRE | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-AQOR | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-AQGO | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-AQGR | 20 (40 μL) | 200 μL |
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| UBA6-CCNA2-20-AQAQ | 20 (40 μL) | 200 μL |
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CCNA2 Gene Summary
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle. This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M. [provided by RefSeq, Aug 2016]
Gene Name: Cyclin A2
Chromosome: CHR4: 122737598 -122745088
Locus: 4q27
UBA6 Gene Summary
Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM, Mar 2008]
Gene Name: Ubiquitin Like Modifier Activating Enzyme 6
Chromosome: CHR4: 68481478 -68566889
Locus: 4q13.2
Gene Diseases
The UBA6 CCNA2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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