UBA2-MIER2 Fusion FISH Probe
The UBA2-MIER2 Fusion FISH Probe is used to confirm a fusion of the UBA2 and MIER2 genes. The fusion of the UBA2 and MIER2 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UBA2-MIER2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-RERE | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-REOR | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-REGO | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-REGR | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-REAQ | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-ORRE | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-OROR | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-ORGO | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-ORAQ | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-GORE | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-GOOR | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-GOGO | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-GOGR | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-GOAQ | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-GRRE | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-GROR | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-GRGO | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-GRGR | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-GRAQ | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-AQRE | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-AQOR | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-AQGO | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-AQGR | 20 (40 μL) | 200 μL |
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| UBA2-MIER2-20-AQAQ | 20 (40 μL) | 200 μL |
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UBA2 Gene Summary
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]
Gene Name: Ubiquitin Like Modifier Activating Enzyme 2
Chromosome: CHR19: 34919267 -34960798
Locus: 19q13.11
MIER2 Gene Summary
The MIER Family Member 2 (MIER2) gene is located on chr19 :305574-344791 at 19p13.3.
Gene Name: MIER Family Member 2
Chromosome: CHR19: 305574 -344791
Locus: 19p13.3
Gene Diseases
The UBA2 MIER2 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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