TYK2-TMEM205 Fusion FISH Probe
The TYK2-TMEM205 Fusion FISH Probe is used to confirm a fusion of the TYK2 and TMEM205 genes. The fusion of the TYK2 and TMEM205 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TYK2-TMEM205-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-RERE | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-REOR | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-REGO | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-REGR | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-REAQ | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-ORRE | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-OROR | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-ORGO | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-ORAQ | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-GORE | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-GOOR | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-GOGO | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-GOGR | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-GOAQ | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-GRRE | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-GROR | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-GRGO | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-GRGR | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-GRAQ | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-AQRE | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-AQOR | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-AQGO | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-AQGR | 20 (40 μL) | 200 μL |
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| TYK2-TMEM205-20-AQAQ | 20 (40 μL) | 200 μL |
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TYK2 Gene Summary
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]
Gene Name: Tyrosine Kinase 2
Chromosome: CHR19: 10461203 -10491248
Locus: 19p13.2
TMEM205 Gene Summary
The Transmembrane Protein 205 (TMEM205) gene is located on chr19 :11453451-11456981 at 19p13.2.
Gene Name: Transmembrane Protein 205
Chromosome: CHR19: 11453451 -11456981
Locus: 19p13.2
Gene Diseases
The TYK2 TMEM205 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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