TUSC2-RASSF1 Fusion FISH Probe
The TUSC2-RASSF1 Fusion FISH Probe is used to confirm a fusion of the TUSC2 and RASSF1 genes. The fusion of the TUSC2 and RASSF1 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TUSC2-RASSF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-RERE | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-REOR | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-REGO | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-REGR | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-REAQ | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-ORRE | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-OROR | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-ORGO | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-GORE | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-GOOR | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-GOGO | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-GOGR | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-GRRE | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-GROR | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-GRGO | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-GRGR | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-AQRE | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-AQOR | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-AQGO | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-AQGR | 20 (40 μL) | 200 μL |
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| TUSC2-RASSF1-20-AQAQ | 20 (40 μL) | 200 μL |
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RASSF1 Gene Summary
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]
Gene Name: Ras Association Domain Family Member 1
Chromosome: CHR3: 50367216 -50378367
Locus: 3p21.31
TUSC2 Gene Summary
This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008]
Gene Name: Tumor Suppressor Candidate 2
Chromosome: CHR3: 50362340 -50365668
Locus: 3p21.31
Gene Diseases
The TUSC2 RASSF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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