TULP3-UGCG Fusion FISH Probe
The TULP3-UGCG Fusion FISH Probe is used to confirm a fusion of the TULP3 and UGCG genes. The fusion of the TULP3 and UGCG genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TULP3-UGCG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-RERE | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-REOR | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-REGO | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-REGR | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-REAQ | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-ORRE | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-OROR | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-ORGO | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-ORAQ | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-GORE | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-GOOR | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-GOGO | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-GOGR | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-GOAQ | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-GRRE | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-GROR | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-GRGO | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-GRGR | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-GRAQ | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-AQRE | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-AQOR | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-AQGO | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-AQGR | 20 (40 μL) | 200 μL |
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| TULP3-UGCG-20-AQAQ | 20 (40 μL) | 200 μL |
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TULP3 Gene Summary
This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009]
Gene Name: Tubby Like Protein 3
Chromosome: CHR12: 3000032 -3050306
Locus: 12p13.33
UGCG Gene Summary
This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014]
Gene Name: UDP-glucose Ceramide Glucosyltransferase
Chromosome: CHR9: 114659205 -114695433
Locus: 9q31.3
Gene Diseases
The TULP3 UGCG Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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