TUBGCP4-TMEM62 Fusion FISH Probe
The TUBGCP4-TMEM62 Fusion FISH Probe is used to confirm a fusion of the TUBGCP4 and TMEM62 genes. The fusion of the TUBGCP4 and TMEM62 genes has been associated with Bladder Urothelial Carcinoma, and Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TUBGCP4-TMEM62-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TUBGCP4-TMEM62-20-AQAQ | 20 (40 μL) | 200 μL |
|
TUBGCP4 Gene Summary
This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
Gene Name: Tubulin Gamma Complex Associated Protein 4
Chromosome: CHR15: 43663312 -43698240
Locus: 15q15.3
TMEM62 Gene Summary
The Transmembrane Protein 62 (TMEM62) gene is located on chr15 :43425721-43477341 at 15q15.2.
Gene Name: Transmembrane Protein 62
Chromosome: CHR15: 43425721 -43477341
Locus: 15q15.2
Gene Diseases
The TUBGCP4 TMEM62 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|