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TTYH3-ASPSCR1 Fusion FISH Probe

The TTYH3-ASPSCR1 Fusion FISH Probe is used to confirm a fusion of the TTYH3 and ASPSCR1 genes. The fusion of the TTYH3 and ASPSCR1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TTYH3-ASPSCR1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-RERE 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-REOR 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-REGO 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-REGR 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-REAQ 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-ORRE 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-OROR 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-ORGO 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-ORAQ 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-GORE 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-GOOR 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-GOGO 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-GOGR 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-GOAQ 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-GRRE 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-GROR 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-GRGO 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-GRGR 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-GRAQ 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-AQRE 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-AQOR 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-AQGO 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-AQGR 20 (40 μL) 200 μL
TTYH3-ASPSCR1-20-AQAQ 20 (40 μL) 200 μL

ASPSCR1 Gene Summary

The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011]

Gene Name: ASPSCR1, UBX Domain Containing Tether For SLC2A4

Chromosome: CHR17: 79935425 -79975282

Locus: 17q25.3

TTYH3 Gene Summary

This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel. [provided by RefSeq, Jul 2008]

Gene Name: Tweety Family Member 3

Chromosome: CHR7: 2671602 -2704436

Locus: 7p22.3

Gene Diseases

The TTYH3 ASPSCR1 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.