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TTC27-SPAST Fusion FISH Probe

The TTC27-SPAST Fusion FISH Probe is used to confirm a fusion of the TTC27 and SPAST genes. The fusion of the TTC27 and SPAST genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TTC27-SPAST-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TTC27-SPAST-20-RERE 20 (40 μL) 200 μL
TTC27-SPAST-20-REOR 20 (40 μL) 200 μL
TTC27-SPAST-20-REGO 20 (40 μL) 200 μL
TTC27-SPAST-20-REGR 20 (40 μL) 200 μL
TTC27-SPAST-20-REAQ 20 (40 μL) 200 μL
TTC27-SPAST-20-ORRE 20 (40 μL) 200 μL
TTC27-SPAST-20-OROR 20 (40 μL) 200 μL
TTC27-SPAST-20-ORGO 20 (40 μL) 200 μL
TTC27-SPAST-20-ORAQ 20 (40 μL) 200 μL
TTC27-SPAST-20-GORE 20 (40 μL) 200 μL
TTC27-SPAST-20-GOOR 20 (40 μL) 200 μL
TTC27-SPAST-20-GOGO 20 (40 μL) 200 μL
TTC27-SPAST-20-GOGR 20 (40 μL) 200 μL
TTC27-SPAST-20-GOAQ 20 (40 μL) 200 μL
TTC27-SPAST-20-GRRE 20 (40 μL) 200 μL
TTC27-SPAST-20-GROR 20 (40 μL) 200 μL
TTC27-SPAST-20-GRGO 20 (40 μL) 200 μL
TTC27-SPAST-20-GRGR 20 (40 μL) 200 μL
TTC27-SPAST-20-GRAQ 20 (40 μL) 200 μL
TTC27-SPAST-20-AQRE 20 (40 μL) 200 μL
TTC27-SPAST-20-AQOR 20 (40 μL) 200 μL
TTC27-SPAST-20-AQGO 20 (40 μL) 200 μL
TTC27-SPAST-20-AQGR 20 (40 μL) 200 μL
TTC27-SPAST-20-AQAQ 20 (40 μL) 200 μL

SPAST Gene Summary

This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4. [provided by RefSeq, Jul 2008]

Gene Name: Spastin

Chromosome: CHR2: 32288679 -32382706

Locus: 2p22.3

TTC27 Gene Summary

The Tetratricopeptide Repeat Domain 27 (TTC27) gene is located on chr2 :32853086-33046118 at 2p22.3.

Gene Name: Tetratricopeptide Repeat Domain 27

Chromosome: CHR2: 32853086 -33046118

Locus: 2p22.3

Gene Diseases

The TTC27 SPAST Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.