TTC27-SPAST Fusion FISH Probe
The TTC27-SPAST Fusion FISH Probe is used to confirm a fusion of the TTC27 and SPAST genes. The fusion of the TTC27 and SPAST genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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TTC27-SPAST-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-RERE | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-REOR | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-REGO | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-REGR | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-REAQ | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-ORRE | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-OROR | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-ORGO | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-ORAQ | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-GORE | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-GOOR | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-GOGO | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-GOGR | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-GOAQ | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-GRRE | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-GROR | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-GRGO | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-GRGR | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-GRAQ | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-AQRE | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-AQOR | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-AQGO | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-AQGR | 20 (40 μL) | 200 μL | ||
TTC27-SPAST-20-AQAQ | 20 (40 μL) | 200 μL |
SPAST Gene Summary
This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4. [provided by RefSeq, Jul 2008]
Gene Name: Spastin
Chromosome: CHR2: 32288679 -32382706
Locus: 2p22.3
TTC27 Gene Summary
The Tetratricopeptide Repeat Domain 27 (TTC27) gene is located on chr2 :32853086-33046118 at 2p22.3.
Gene Name: Tetratricopeptide Repeat Domain 27
Chromosome: CHR2: 32853086 -33046118
Locus: 2p22.3
Gene Diseases
The TTC27 SPAST Fusion has been associated with the following diseases:
Disease Name |
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Lung Squamous Cell Carcinoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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