TTC17-API5 Fusion FISH Probe
The TTC17-API5 Fusion FISH Probe is used to confirm a fusion of the TTC17 and API5 genes. The fusion of the TTC17 and API5 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TTC17-API5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-RERE | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-REOR | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-REGO | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-REGR | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-REAQ | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-ORRE | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-OROR | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-ORGO | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-ORAQ | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-GORE | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-GOOR | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-GOGO | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-GOGR | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-GOAQ | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-GRRE | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-GROR | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-GRGO | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-GRGR | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-GRAQ | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-AQRE | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-AQOR | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-AQGO | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-AQGR | 20 (40 μL) | 200 μL |
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| TTC17-API5-20-AQAQ | 20 (40 μL) | 200 μL |
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API5 Gene Summary
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Name: Apoptosis Inhibitor 5
Chromosome: CHR11: 43333504 -43366080
Locus: 11p12
TTC17 Gene Summary
The Tetratricopeptide Repeat Domain 17 (TTC17) gene is located on chr11 :43380434-43516483 at 11p12-p11.2.
Gene Name: Tetratricopeptide Repeat Domain 17
Chromosome: CHR11: 43380434 -43516483
Locus: 11p12-p11.2
Gene Diseases
The TTC17 API5 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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