TSSC4-LSP1 Fusion FISH Probe
The TSSC4-LSP1 Fusion FISH Probe is used to confirm a fusion of the TSSC4 and LSP1 genes. The fusion of the TSSC4 and LSP1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSSC4-LSP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-RERE | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-REOR | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-REGO | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-REGR | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-REAQ | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-ORRE | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-OROR | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-ORGO | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-GORE | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-GOOR | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-GOGO | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-GOGR | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-GRRE | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-GROR | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-GRGO | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-GRGR | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-AQRE | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-AQOR | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-AQGO | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-AQGR | 20 (40 μL) | 200 μL |
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| TSSC4-LSP1-20-AQAQ | 20 (40 μL) | 200 μL |
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LSP1 Gene Summary
This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Lymphocyte-specific Protein 1
Chromosome: CHR11: 1874199 -1913493
Locus: 11p15.5
TSSC4 Gene Summary
This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Name: Tumor Suppressing Subtransferable Candidate 4
Chromosome: CHR11: 2423522 -2425106
Locus: 11p15.5
Gene Diseases
The TSSC4 LSP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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