TSPO-CDH18 Fusion FISH Probe
The TSPO-CDH18 Fusion FISH Probe is used to confirm a fusion of the TSPO and CDH18 genes. The fusion of the TSPO and CDH18 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSPO-CDH18-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-RERE | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-REOR | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-REGO | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-REGR | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-REAQ | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-ORRE | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-OROR | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-ORGO | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-GORE | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-GOOR | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-GOGO | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-GOGR | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-GRRE | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-GROR | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-GRGO | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-GRGR | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-AQRE | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-AQOR | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-AQGO | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-AQGR | 20 (40 μL) | 200 μL |
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| TSPO-CDH18-20-AQAQ | 20 (40 μL) | 200 μL |
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TSPO Gene Summary
Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012]
Gene Name: Translocator Protein
Chromosome: CHR22: 43547534 -43559248
Locus: 22q13.2
CDH18 Gene Summary
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Name: Cadherin 18
Chromosome: CHR5: 19473154 -19988353
Locus: 5p14.3
Gene Diseases
The TSPO CDH18 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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