TSPAN9-PRH1 Fusion FISH Probe
The TSPAN9-PRH1 Fusion FISH Probe is used to confirm a fusion of the TSPAN9 and PRH1 genes. The fusion of the TSPAN9 and PRH1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSPAN9-PRH1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-RERE | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-REOR | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-REGO | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-REGR | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-REAQ | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-ORRE | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-OROR | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-ORGO | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-GORE | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-GOOR | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-GOGO | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-GOGR | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-GRRE | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-GROR | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-GRGO | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-GRGR | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-AQRE | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-AQOR | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-AQGO | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-AQGR | 20 (40 μL) | 200 μL |
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| TSPAN9-PRH1-20-AQAQ | 20 (40 μL) | 200 μL |
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PRH1 Gene Summary
This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. Multiple distinct alleles of this locus including the parotid isoelectric-focusing variant slow (PIF-s), the parotid acidic protein (Pa), and the double band slow (Db-s) isoforms have been characterized. The reference genome encodes the Db-s allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. Co-transcription of this gene with adjacent genes has been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]
Gene Name: Proline Rich Protein HaeIII Subfamily 1
Chromosome: CHR12: 11033559 -11036874
Locus: 12p13.2
TSPAN9 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Nov 2009]
Gene Name: Tetraspanin 9
Chromosome: CHR12: 3186520 -3395730
Locus: 12p13.33-p13.32
Gene Diseases
The TSPAN9 PRH1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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