TSPAN9-KRT7 Fusion FISH Probe
The TSPAN9-KRT7 Fusion FISH Probe is used to confirm a fusion of the TSPAN9 and KRT7 genes. The fusion of the TSPAN9 and KRT7 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSPAN9-KRT7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-RERE | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-REOR | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-REGO | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-REGR | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-REAQ | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-ORRE | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-OROR | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-ORGO | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-GORE | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-GOOR | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-GOGO | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-GOGR | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-GRRE | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-GROR | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-GRGO | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-GRGR | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-AQRE | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-AQOR | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-AQGO | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-AQGR | 20 (40 μL) | 200 μL |
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| TSPAN9-KRT7-20-AQAQ | 20 (40 μL) | 200 μL |
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KRT7 Gene Summary
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
Gene Name: Keratin 7
Chromosome: CHR12: 52626953 -52642709
Locus: 12q13.13
TSPAN9 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Nov 2009]
Gene Name: Tetraspanin 9
Chromosome: CHR12: 3186520 -3395730
Locus: 12p13.33-p13.32
Gene Diseases
The TSPAN9 KRT7 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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